Designing typical genes with Odysseus

If Odysseus is helpful for your research, please cite:

Simm D., Popova B., Braus G. H., Waack S. and Kollmar M. (2021) Design of typical genes for heterologous gene expression.
Scientific Reports. 12(9625). DOI_disc_logo - 10.1038/s41598-022-13089-1

Quick Start Guide

Sequence Input Mask

Example data: Protein or CDS sequences

Exclude Restriction Enzymes (grouped by prototype)

computation intensive

Set stability level (RNAfold: Minimum free energy)


Result: Synonymous gene sequences adapted to "..."

Restrictions and License

Using Odysseus by non-academics requires permission. Odysseus may be obtained upon request and used under a Creative Commons BY-NC-SA 4.0 International License.